XProtect Professional 2018 R2 migration?

Is it even possible to perform a XProtect Professional 2018 R2 migration?

The guide that I have managed to find is based on Professional 2014 with the security updates certain registry keys are now missing. Is there no alternate, other than doing a clean installation?

As this does not pertain to development but to a general situation you will most likely get better help from the partners active in the Support Community - https://supportcommunity.milestonesys.com